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Mutation Accumulation & Molecular Clock Simulator

Education

Evolve DNA sequences along two diverging lineages and compare the true number of changes with what you can actually observe, which saturates because of multiple hits at the same site. The Jukes-Cantor and Kimura corrections recover the true distance, and the molecular clock turns that distance into an estimate of when the lineages split. Presets with cited human, bacterial and viral mutation rates ground the numbers, and a calibration tool shows how rate variation across lineages can break a strict clock.

Open Mutation Accumulation & Molecular Clock Simulator (mutationrate.apps.vtc.com)

About Mutation Accumulation & Molecular Clock Simulator

Mutation Accumulation & Molecular Clock Simulator is an interactive learning tool on VTC. Evolve DNA sequences along two diverging lineages and compare the true number of changes with what you can actually observe, which saturates because of multiple hits at the same site. The Jukes-Cantor and Kimura corrections recover the true distance, and the molecular clock turns that distance into an estimate of when the lineages split. Presets with cited human, bacterial and viral mutation rates ground the numbers, and a calibration tool shows how rate variation across lineages can break a strict clock. It runs in your web browser and is free to use, and suits students, teachers and self-learners.

Who it's for: Students, teachers and self-learners

Features

Frequently asked questions

What is Mutation Accumulation & Molecular Clock Simulator on VTC?

Mutation Accumulation & Molecular Clock Simulator is an interactive learning tool on VTC. Evolve DNA sequences along two diverging lineages and compare the true number of changes with what you can actually observe, which saturates because of multiple hits at the same site. The Jukes-Cantor and Kimura corrections recover the true distance, and the molecular clock turns that distance into an estimate of when the lineages split.

Is Mutation Accumulation & Molecular Clock Simulator free to use?

Yes. The VTC app catalog lists Mutation Accumulation & Molecular Clock Simulator at no cost, and it runs in your web browser with nothing to install.

Who is Mutation Accumulation & Molecular Clock Simulator for and how do I start?

It is aimed at students, teachers and self-learners. To start, open https://mutationrate.apps.vtc.com in your browser.