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Pairwise Sequence Alignment Tool

Education

Align two sequences with global (Needleman-Wunsch) or local (Smith-Waterman) alignment and watch the dynamic-programming table fill step by step, with the traceback path lighting up the final alignment. Use DNA scoring or real BLOSUM62, set affine gap penalties, and step through all equally good alignments instead of just the first. The tool re-scores every alignment it returns to check it against the table, and three depth levels run from the idea of lining sequences up to the full recurrences.

Open Pairwise Sequence Alignment Tool (sequencealignment.apps.vtc.com)

About Pairwise Sequence Alignment Tool

Pairwise Sequence Alignment Tool is an interactive learning tool on VTC. Align two sequences with global (Needleman-Wunsch) or local (Smith-Waterman) alignment and watch the dynamic-programming table fill step by step, with the traceback path lighting up the final alignment. Use DNA scoring or real BLOSUM62, set affine gap penalties, and step through all equally good alignments instead of just the first. The tool re-scores every alignment it returns to check it against the table, and three depth levels run from the idea of lining sequences up to the full recurrences. It runs in your web browser and is free to use, and suits students, teachers and self-learners.

Who it's for: Students, teachers and self-learners

Features

Frequently asked questions

What is Pairwise Sequence Alignment Tool on VTC?

Pairwise Sequence Alignment Tool is an interactive learning tool on VTC. Align two sequences with global (Needleman-Wunsch) or local (Smith-Waterman) alignment and watch the dynamic-programming table fill step by step, with the traceback path lighting up the final alignment. Use DNA scoring or real BLOSUM62, set affine gap penalties, and step through all equally good alignments instead of just the first.

Is Pairwise Sequence Alignment Tool free to use?

Yes. The VTC app catalog lists Pairwise Sequence Alignment Tool at no cost, and it runs in your web browser with nothing to install.

Who is Pairwise Sequence Alignment Tool for and how do I start?

It is aimed at students, teachers and self-learners. To start, open https://sequencealignment.apps.vtc.com in your browser.